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Vertex Pharmaceuticals
VRTX · NASDAQBiotechnology
The economic chain
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Raw inputs
Equipment
Foundry
Chip design
Software
AI demand
Discovery & IPTargets, chemistry, gene-…Activeingredients &…APIs, cell-therapy manufa…Trials &approvalClinical development, reg…MedicinesVertex's franchisesPayers &channelHealth systems, PBMs, dis…PatientsWho the medicine reachesR&DVertex R&DCRSPCRISPR TherapeuticsLZALonzaCDMOAPI & CDMO partnersREGFDA / EMAVRTXVertex PharmaceuticalsTRKTrikafta / KaftrioALYAlyftrekCASCasgevyJRVJournavxPAYPayers & health systemsCFCF patientsRXRare & specialty patients
Company details
Market cap
$115B
P/E ratio
26×
Div yield
0%
Revenue
$12B
Net income
$4B
Rev. growth
+8%
Cash & securities
$13B
2026 rev. guidance
~$13B
In plain English
Vertex owns cystic fibrosis: its Trikafta/Kaftrio and next-generation Alyftrek pills treat the underlying disease for the vast majority of CF patients worldwide and throw off ~$12B a year. It is now spending that cash to diversify — Casgevy, the first approved CRISPR gene-editing therapy (co-developed with CRISPR Therapeutics), the non-opioid pain drug Journavx, an islet-cell therapy aiming to cure type-1 diabetes, and a kidney-disease pipeline bought via Alpine Immune.
In simple terms
What Vertex Pharmaceuticals really sells
Vertex owns cystic fibrosis: its Trikafta/Kaftrio and next-generation Alyftrek pills treat the underlying disease for the vast majority of CF patients worldwide and throw off ~$12B a year. It is now spending that cash to diversify — Casgevy, the first approved CRISPR gene-editing therapy (co-developed with CRISPR Therapeutics), the non-opioid pain drug Journavx, an islet-cell therapy aiming to cure type-1 diabetes, and a kidney-disease pipeline bought via Alpine Immune.
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Risk read
Moderate
SteadierMore speculative
Why this rating?